Seminar: Investigation on the mechanisms via which air pollution exposure affecting human health through the intervention studies

when: 29 August, 2019 14:00 PM
where: Hahn-Meitner-Weg 1 55128 Mainz

Dr. Jicheng Gong, College of Environmental Sciences and Engineering, Peking University (Host H. Su)

The seminar takes place on Thursday 29th August at 14.00 in the confernce room of the MPI for Chemistry.

Abstract

Air pollution has been well recognized as an important factor that can adversely affect human’s cardio-pulmonary health. But the underlying mechanisms via which the pollutants induce the health effects are still not well known. The complex compositions of the air pollution have unavoidable confounding effects when studying one certain pollutant’s effect, resulting in the causal inference on the relationships difficult. The intervention study could generate a relatively controlled condition with the confounding factors not changed much across the intervention periods, which could increase the ability of making causal inference when studying the associations between air pollutants and human health.

In the lecture, Jicheng Gong will introduce two intervention studies that focus on either traffic-related pollutants or the indoor air pollution exposure. In both studies, the exposure to the air pollution were controlled through walking in locations with different exposure levels, or through a particulate filtration unit. It’s been found that the traffic-emitted pollutants could reduce the beneficial effects on the cardio-respiratory system while walking to both normal subjects and those with cardio-pulmonary diseases; and the reduction in personal indoor ozone exposure was significantly related with thrombosis and systemic inflammatory responses.